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Chorionic Gonadotrophin by Gufic is a sports drug that belongs to the group of peptide hormones. This drug, although not approved in sports pharmacology due to its doping status, is used in women during pregnancy, stimulating the production of progesterone and estradiol, and in men, increasing the efficiency of testosterone synthesis.
The drug is presented in the form of a porous dry substance for intramuscular administration. It contains chorionic gonadotropin as an active substance and mannitol as an auxiliary substance. This drug is in demand due to its affordable cost, which facilitates its regular use.
Medical indications for taking Human Chorionic Gonadotropin
- hypogonadotropic hypogonadism;
- decreased reproductive function associated with dyspermia;
- in case of slow sexual development of boys, which is associated with gonadotropic dysfunction of the pituitary cells;
- cryptorchidism (for medical purposes);
- In sports, it is most often taken to restore testosterone production (although this effect is used not only in sports).
Women take this drug in the following cases:
- when undergoing assisted reproductive technology programs;
- ovulation induction, in cases of infertility, etc.
Pharmacological action of human chorionic gonadotropin
The pharmacological action consists of stimulating the development of the sexual organs and secondary sexual characteristics. In men, it promotes increased testosterone production and stimulates spermatogenesis, while in women, it causes ovulation and the synthesis of progesterone and estrogens.
Use and dosage of Human Chorionic Gonadotropin
The dosage of the drug should be selected by the doctor individually, taking into account the characteristics of the body. A cycle of less than 6 weeks and in minimal doses does not require the use of Chorionic Gonadotropin 5000 IU. With higher doses and long-term use, two injections per week (300-500 IU) are prescribed. Injections are made every other day for 3 weeks. Ls The highest concentration of the drug is observed 5-12 hours after administration, and is excreted within 30 hours through the kidneys. Steroid courses of three months require the use of hCG almost on a permanent basis, 4-5 weeks of the course, and 2 weeks of rest.
Side effects
Men may experience the following negative effects: fluid accumulation in the body, sodium imbalance, stimulation of androgen production by the body, changes in the tissues of the prostate gland, gynecomastia, a significant increase in testosterone production, resulting in an increase in the frequency of erections, increased sensitivity (hypersensitivity) of the nipples, and some other changes.
Both women and men may experience the following adverse reactions: pain, swelling, itching at the injection site, rash, and fever.
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