Evoforce 200 strip of 10 tabs (200 mg/1 tab)

Evoforce 200 (Sildenafil Citrate) by Evolve Biolabs - contains 200 mg of sildenafil, a powerful PDE5 inhibitor used to treat erectile dysfunction (ED) by increasing blood flow to the penis, which helps men achieve and maintain a firm erection. This highly concentrated formula is designed for those who require a higher dosage for optimal effects and results.

Effects of taking Evoforce

• effectively treats erectile dysfunction (ED) by improving blood circulation;
• helps improve sexual stamina and performance;
• may be prescribed for pulmonary arterial hypertension (PAH) under the supervision of a physician.

Medical indications for taking Evoforce

Sildenafil is an oral medication used to treat erectile dysfunction. When sexually aroused, the drug restores decreased erectile function by increasing blood flow to the penis.

The physiological mechanism that leads to erection involves the release of nitric oxide (NO) in the corpora cavernosa during sexual arousal. The released nitric oxide activates the enzyme guanylate cyclase, which stimulates an increase in cyclic guanosine monophosphate (cGMP), which in turn causes relaxation of the smooth muscles of the corpora cavernosa, facilitating blood flow.

Usage and dosage of Evoforce

The recommended dose of the drug is 50 mg and is used, if necessary, approximately one hour before sexual intercourse. Depending on the effectiveness and tolerability of the drug, the dose can be increased to 100 mg or decreased to 25 mg. The maximum recommended dose is 100 mg. The maximum recommended frequency of use of the drug is once a day. When using the drug during meals, the effect of the drug may occur later than when used on an empty stomach.

Elderly patients.

There is no need for dose adjustment in elderly patients (≥65 years).

Patients with renal insufficiency.

For patients with mild to moderate renal impairment (creatinine clearance 30 to 80 ml/min), the recommended dose is the same as that indicated above in the Adults section.

Since sildenafil clearance is reduced in patients with severe renal impairment (creatinine clearance below 30 ml/min), the recommended dose is 25 mg. Depending on the efficacy and tolerability of the drug, the dose can be increased to 50 mg and 100 mg.

Patients with liver failure.

Since sildenafil clearance is reduced in patients with liver failure (cirrhosis), the recommended dose is 25 mg. Depending on the efficacy and tolerability of the drug, the dose can be increased to 50 mg and 100 mg.

Side effects

The most commonly reported adverse reactions were headache, flushing, dyspepsia, nasal congestion, back pain, dizziness, nausea, hot flushes, visual disturbances, cyanopsia, and blurred vision.

Overdose

When using a single dose of sildenafil up to 800 mg, adverse reactions were similar to those observed with lower doses of sildenafil, but were more frequent and severe. Using sildenafil at a dose of 200 mg did not increase efficacy, but caused an increase in the incidence of adverse reactions (headache, flushing, dizziness, dyspepsia, nasal congestion, visual disturbances).

In case of overdose, if necessary, resort to the usual supportive measures. Acceleration of sildenafil clearance during hemodialysis is unlikely due to the high degree of binding of the drug to plasma proteins and the lack of elimination of sildenafil in the urine.