T4 (Levothyroxine Sodium) by Somatrop Lab has a powerful fat-burning effect, increases calorie expenditure, and speeds up metabolism. Its popularity has declined recently due to its negative effects on the heart; thyroxine has an adrenaline-like impact, causing the heart to beat more frequently, and along with this causes feelings of excitement and anxiety that are not well tolerated.
However, many of the side effects can be eliminated when thyroxine and beta-blockers are combined. Beta-blockers inhibit the receptors through which thyroxine affects the heart, so they prevent the negative effects of thyroxine on the heart, normalize the rhythm and reduce the occurrence of some other side effects of thyroxine.
Many people believe that the drug can irreversibly suppress the function of their own thyroid gland, but in studies, it has been shown that even large doses of the drug for 3 weeks of administration reduce the secretion of its own hormones by only 20%, while after 4 weeks the secretion returned to normal.
Effects of taking T4 Levothyroxine sodium
- acceleration of metabolism;
- increased heat production;
- fat burning;
- stimulating effect on the central nervous system;
- appetite suppression;
- decreased need for sleep;
- increasing physical performance.
Medical indications for taking T4 Levothyroxine sodium
Levothyroxine is a drug used to treat an underactive thyroid (hypothyroidism) and other conditions where a person's production of thyroid hormones is lower than normal. Levothyroxine sodium replaces or provides support for thyroid hormones that are normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or as a result of radiation/drug damage to the thyroid gland or surgical removal of the thyroid gland. Levothyroxine is also known as L-thyroxine or T4.
Patients receiving human growth hormone (HGH) should take T4 to prevent HGH deficiency, as HGH significantly increases the conversion of T4 to T3, which can cause pathological T4 deficiency.
Application and dosage of T4 Levothyroxine sodium
- Start taking Levothyroxine sodium (Thyroxine) with 50 mcg per day, 2 times a day (25 mcg each) in the first half of the day. In the morning, take 25 mg of metoprolol (a beta blocker that relieves heart strain and palpitations) if your heart rate is above 70 bpm after lunch. per minute at rest, then take another 25 mg of metoprolol.
- Gradually increase the dose to 150-300 mcg per day, 3 times a day until 18:00. Increase the daily dose of Metoprolol to 100 mg (2 times a day, 50 mg). The dosage of metoprolol is selected individually so that the resting heart rate is 60-70 beats. in a minute.
- Reduce the dose of thyroxine if severe side effects occur.
- Monitor your heart rate; if your resting heart rate is above 80, increase the dose of metoprolol by 25 mg; if your resting heart rate is below 60 beats per minute, reduce the dose of metoprolol by 25 mg.
- Monitor your blood pressure, it should not be higher than 140/90 mm Hg. Art. Metoprolol helps lower blood pressure.
- Course duration is 4-7 weeks.
- Do not stop taking thyroxine suddenly: start reducing the dose 2 weeks before the end of the cycle, continue the gradual reduction until it is completely stopped.
- If you have diarrhea, include loperamide in your course, 1-2 capsules per day.
- The minimum break after completing the course is 3-4 weeks.
If heaviness in the heart area occurs, it is better to add Asparkam in addition to Metoprolol. 4-6 tablets per day, divided into 2-3 doses, after meals. It would also be a good idea to improve your heart function with Riboxin. 2-4 tablets at a time, 2-3 times a day. Riboxin will improve the energy balance of the myocardium, and Asparkam will become a source of Potassium and Magnesium, necessary to maintain normal heart rhythm.
Side effects
- tachycardia (palpitations), increased blood pressure - eliminated by beta-blockers;
- osteoporosis;
- diarrhea - eliminated by loperamide;
- excitement;
- insomnia;
- muscle tremors;
- dry mouth;
- sweating;
- the feeling of heat;
- decreased thyroid function (occurs with long courses and very high doses of thyroxine; when using recommended doses, the function is restored after 3-4 weeks);
- allergic rash.
A detailed description of side effects can be found in the instructions. It is also necessary to consult a specialist to identify contraindications.
What to Avoid
Theoretically, long-term use of high doses can lead to serious problems with the thyroid gland and suppression of endogenous hormone production. Studies show a reduction of approximately 20% after 3 weeks of use. However, when used correctly at recommended doses, thyroid function is restored within 3–4 weeks. Levothyroxine has adrenaline-promoting effects, including increased heart rate and nervousness, which can be avoided with beta-blockers.
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