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Semaglutide Pen from Hilma Biocare has become a real breakthrough in the pharmacotherapy of obesity. It is the first drug that has shown a sustained and significant reduction in body weight in overweight people in large clinical trials — without the need for surgery. In an international study, patients taking semaglutide lost an average of up to 15% of their initial body weight, on a standard diet and with moderate exercise. In comparison, the placebo group lost no more than 2-3%. Today, this drug has also become available to a wide range of patients.
Effects of taking Semaglutide
- helps control blood sugar levels in type 2 diabetes;
- promotes clinically proven weight loss;
- may reduce the risk of cardiovascular complications;
- A convenient pen-like device allows you to accurately dose the drug and administer it yourself under the supervision of a doctor.
Pharmacological action of Semaglutide
Semaglutide acts through the incretin pathway – like GLP-1, it affects the receptors of the hormone glucagon. It suppresses the secretion of glucagon by the islets of Langerhans in the pancreas, which stimulates the secretion of insulin and leads to a decrease in the level of glucose and glycated hemoglobin in the blood.
Semaglutide also reduces the patient's energy intake by reducing appetite, food cravings, and changing food preferences to lower calorie diets.
How does Semaglutide work?
Semaglutide pen works by mimicking the action of GLP-1, a natural hormone in the body. This action includes:
- stimulation of insulin secretion in response to elevated blood sugar levels;
- reducing the release of glucagon, preventing excess glucose production;
- slowing down gastric emptying to maintain feelings of fullness and control appetite.
Through these combined mechanisms, semaglutide promotes long-term glycemic control and weight management.
Use and dosage of Semaglutide
Semaglutide pen 5 mg is usually administered subcutaneously once weekly. The dosage is adjusted by the doctor based on the patient's needs. It is essential to follow the doctor's instructions and refrain from experimenting on your own.
Side effects
General:
- nausea, vomiting, constipation, diarrhea;
- mild abdominal discomfort.
Less common but serious:
- risk of pancreatitis;
- gallbladder problems;
- Rare cases of hypoglycemia occur when combined with other drugs for the treatment of diabetes.
People with a history of thyroid tumors or MEN-2 syndrome should avoid taking this drug.
Who should not use Semaglutide?
patients with a personal or family history of thyroid cancer;
persons with pancreatitis or gallbladder disease;
pregnant and lactating women;
persons not under constant medical supervision.
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